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researcher / Nicolas Winssinger

Nicolas Winssinger

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Disciplines:

Chemistry

Organic chemistry

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Directed Thesis:

Nouvelles approches vers les lactones sesquiterpéniques

High-throughput synthesis of chemical libraries based on families of natural bioactive substances

Synthesis of modified peptide nucleic acids

DNA display : a novel strategy for the rapid selection of small molecule ligands

Extending the diversity of privileged natural product motifs : Synthesis of a library of resorcylic acid lactones and studies towards the guaianes and pseudoguaianes

Emerging functions from nucleic acid programmed self-assemblies

Inhibition of HSP90 with pochoximes : structure-activity relationship and structure-based insights

Divergent synthesis of resorcyclic acid lactones : a privileged natural pharmacophore

PNA as a versatile scafforld for programmable supramolecular chemistry : Applications to encode combinatorial libraries and template reactions

Small molecule microarray : New tool to profile enzymatic activity on a proteomic scale

Diversity-oriented synthesis of pochonins : a privilege scaffold for ATPase and kinase inhibition