Abstract EN:

This thesis presents a study of the relationships between the chemical structure and the organisation of monomers in supramolecular assemblies. We evaluate the physicochemical properties of a new family of bolaamphiphiles by various methods (X-ray diffraction, DSC, transmission electron microscopy and optical microscopy). The dissymmetrical bolaamphiphiles, that we synthesize and investigate, bear a neutral saccharidic polar head and a cationic headgroup derived from glycine betaïne. In aqueous media, these molecules form of vesicles, tubule-like or filaments depending on the size and/or the nature of the hydrophobic skeleton. We also described the synthesis of a bolaamphiphile that contains a nitroxide moiety at the cationic headgroup. The physico-chemical properties of this spin labeled bolaamphiphile were evaluated either in aqueous media. We use this bolaamphiphile to study the dynamics of the molecules into the supramolecular aggregates which are formed by electron paramagnetic resonance spectroscopy (EPR).